Summary: Unsatisfied kinetochore-microtubule attachment activates the spindle assembly checkpoint to inhibit the metaphase-anaphase transition.However, some cells eventually override mitotic arrest by mitotic slippage.Here, we show that inactivation of TORC1 kinase elicits mitotic slippage in budding yeast and ECHINACEA 2+ human cells.Yeast mitotic
Ischemic stroke is one of the leading causes of death among the aged population in the world.Experimental stroke models with rodents play a fundamental role in the Soccer - Balls investigation of the mechanism and impairment of cerebral ischemia.For its celerity and veracity, the 2,3,5-triphenyltetrazolium chloride (TTC) staining of rat brains has
The accurate diagnosis of gout frequently constitutes a challenge in clinical practice, as it bears a close resemblance to other rheumatologic conditions.An undelayed diagnosis and an early therapeutic intervention using uric acid lowering therapy (ULT) is of the utmost importance for preventing bone destruction, the main point of managing gout pat